Association between Serum Ferritin and Thyroid profile in Radiologically proven patients with Goitre with Thyroiditis

---

Original Article

Author Details : Monu Sarin, Poonam Arora, SC Mohapatra

Volume : 4, Issue : 2, Year : 2017

Article Page : 50-52

Suggest article by email

Get Permission

---

Abstract

Introduction: Thyroid peroxidase (TPO) is a membrane-bound glycosylated hemoprotein that has a key role in the biosynthesis of thyroid hormones by organification. Ferritin is an iron storage protein found in almost all of the body tissues. Serum ferritin levels also have been reported to be altered in patients with thyroid disease.
Objective: The aim of this study is to establish a correlation between serum ferritin and thyroid hormones in thyroid disorder patients.
Materials and Method: was a cross sectional study of 80 subjects, visiting medical outpatient department of SGT Medical College and Hospital, Budhera, Gurugram, Haryana. Patients were subjected to ultrasound. Radiologically proven Thyroid disorder patients sample were analysed for the measurement of T₃, T₄, TSH (by CLIA) and Serum Ferritin (by ELISA).

Results: The mean T₃, T₄, TSH and serum ferritin levels showed highly sig­nificant difference with p<0.001 in hypothyroid group compared to controls.
Conclusion: Low serum ferritin levels are associated with hypothyroidism. The estimation of iron storage protein ferritin may help in understanding the pathiphysiology, diagnosis and treatment of thyroid disorders.

Keywords: Serum Ferritin, Thyroid Profile, Hypothyroidism

How to cite : Sarin M, Arora P, Mohapatra S, Association between Serum Ferritin and Thyroid profile in Radiologically proven patients with Goitre with Thyroiditis. J Community Health Manag 2017;4(2):50-52

This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.