MEASUREMENT OF INTRACAMERAL CONCENTRATION OF MOXIFLOXACIN ACHIEVED AFTER TOPICAL APPLICATION OF THE DRUG

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Author Details : Samir Kumar, Diksha Prakash, Reshmee Boodoo, OPS Maurya, Sanjay Singh, Abhishek Chandra

Volume : 2, Issue : 4, Year : 2015

Article Page : 187-194

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Abstract

Aim: To estimate Intracameral concentration of Moxifloxacin applied topically in different schedule.
Methods:  Measurement of moxifloxacin was done in Aqueous aspirated before cataract extraction of different patients instilling topical drug in different schedule.
Results: Significant difference was found between drug concentration of two groups, one instilling single drop of drug 30 min before surgery( 1.20 ± 0.43 µg/ml)  and other, instilling 4 drops a day before and one drop on day of surgery (1.80 ± 0.34 µg/ml).
Conclusion: Instilling moxifloxacin drops 1 day before cataract surgery results in higher concentration and is effective in endophthalmitis prevention.

Key Words: Intracameral , Endophthalmitis, Neutrophils

How to cite : Kumar S, Prakash D, Boodoo R, Maurya O, Singh S, Chandra A, MEASUREMENT OF INTRACAMERAL CONCENTRATION OF MOXIFLOXACIN ACHIEVED AFTER TOPICAL APPLICATION OF THE DRUG. J Community Health Manag 2015;2(4):187-194

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