Human metapneumovirus (hMPV) has been recognized as a significant contributor to acute respiratory tract infections (ARTIs), particularly in young children, elderly individuals, and immune-compromised patients since its discovery in 2001. With clinical manifestations similar to respiratory syncytial virus (RSV), hMPV has been associated with bronchiolitis, pneumonia, and asthma exacerbations, often leading to hospitalizations. Over the years, genetic studies, epidemiological surveillance, and diagnostic advancements have enhanced our understanding of hMPV’s impact. This article provides a chronological review of key research developments on hMPV, emphasizing its prevalence, clinical implications, genetic diversity, and potential therapeutic approaches.
Keywords: Hman metapneumovirus, Acute respiratory infections, Respiratory infections, Pneumonia
